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BRCA1 and BRCA2 gene mutation testing can give several possible results: a positive result, a negative result, or an ambiguous or uncertain result. A positive test result indicates that a person has inherited a known harmful mutation in BRCA1 orBRCA2 and, therefore, has an increased risk of developing certain cancers.

A woman’s lifetime risk of developing breast and/or ovarian cancer is greatly increased if she inherits a harmful mutation in BRCA1 or BRCA2.

Breast cancer: About 12 percent of women in the general population will develop breast cancer sometime during their lives (4). By contrast, according to the most recent estimates, 55 to 65 percent of women who inherit a harmful BRCA1 mutation and around 45 percent of women who inherit a harmful BRCA2 mutation will develop breast cancer by age 70 years (56).

Ovarian cancer: About 1.3 percent of women in the general population will develop ovarian cancer sometime during their lives (4). By contrast, according to the most recent estimates, 39 percent of women who inherit a harmful BRCA1 mutation (56) and 11 to 17 percent of women who inherit a harmful BRCA2mutation will develop ovarian cancer by age 70 years (56).

https://www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet#q1

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